Low dose 5-aminolevulinic acid: Implications in spectroscopic measurements during brain tumor surgery
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منابع مشابه
Low dose 5-aminolevulinic acid: Implications in spectroscopic measurements during brain tumor surgery.
BACKGROUND Using 5-aminolevulinic acid (ALA) as an intraoperative fluorescence contrast has been proven to improve the resection of glioblastoma and contribute to prolonged patient survival. ALA accumulates as protoporphyrin IX (PpIX) in the tumor cells and is administered in an advised dose of 20 mg/kg body weight (b.w.) for brain tumor resection using fluorescence surgical microscopes. PpIX f...
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ژورنال
عنوان ژورنال: Photodiagnosis and Photodynamic Therapy
سال: 2015
ISSN: 1572-1000
DOI: 10.1016/j.pdpdt.2015.03.004